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Jenifer and Angelo Magliocco know much more about spinal muscular atrophy than they ever wanted to. The rare genetic disease killed their first son when he was only 8 weeks old. Before having another child, they used a genetic test to determine if an embryo carried the disease-causing gene.

Fed Chairman Benjamin Bernanke calls for China to reduce its massive trade surplus. Among his suggestions: enact policies to increase China's consumer spending; embrace more flexibility in the exchange rate; and develop more of a 'social safety net', so that households will be less preoccupied with saving and more willing to invest.

Every Monday, Melissa Gray bakes a different cake for her colleagues at NPR. That's nearly 50 confections over the past year, with no repeats, no mixes, no margarine, no low-fat sour cream, no faux sugar. She shares what she's learned.

In a special edition of Talk of the Nation, host Neal Conan talks about the future of deaf education and the controversy surrounding the appointment of the successor to Gallaudet University President I. King Jordan.

For Turkish novelist Orhan Pamuk, winning the 2006 Nobel Prize for Literature completes a turnaround from his being tried on charges of "insulting Turkishness." The charges against Pamuk, Turkey's most internationally renowned novelist, were eventually dropped.

This week, we're diving back into the archives for Part IV of our 25th Year Spectacular! We've got interviews with George Takei, Martha Stewart, Mariska Hargitay, and more!

Turkish novelist Orhan Pamuk wins the Nobel literature prize. Pamuk, 54, gained international acclaim for books including Snow, Istanbul and My Name Is Red. But he has also earned notoriety for legal troubles over his comments on Turkey's past.

The population of the United States has officially reached 300 million. According to government calculations, America reached the milestone at 7:46 a.m. ET on Tuesday. The United States is only the third country in the world to reach 300 million people.

President Bush defends his handling of security and foreign policy, from the U.S. response to North Korea's recent nuclear bomb test to the war in Iraq. Despite polls that show the Republicans struggling in the midterm elections, the president said his party will hold Congress.

There are overdue library books. Then there's An Elementary Treatise on Electricity, which was last checked out in Massachusetts in 1904. It finally made it back after being spotted in West Virginia.