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Scientists are trying to develop drugs to counteract an "undruggable" genetic variant that's responsible for about 30 percent of all cancer cases. It's high risk — high reward research.

David Greene talks to Democratic Sen. Chris Coons of Delaware about the announcement that Nikki Haley will leave her post as U.S. ambassador to the U.N. Mara Liasson weighs in on the conversation.

Is comedy timeless? Comedian Jim Gaffigan explores that question by delivering ancient jokes to an unsuspecting audience.

Plans to expand the border crossing could bulldoze over a longstanding market where many food vendors have made their living — and in some cases, their homes — for years, if not generations.

NPR's Mary Louise Kelly talks with Adm. James Stavridis, former Supreme Allied Commander of NATO, about the NATO summit and the state of the global alliance.

NPR's Noel King speaks to Leonid Volkov, chief of staff to Russian opposition figure Alexei Navalny, as President Biden and Russian President Vladimir Putin hold a summit in Geneva.

It's been two years since the R&B singer and songwriter was arrested. His first federal trial is about to begin in New York, but a lot has happened in the interim. Here's what you've missed.

NIH scientists are looking for people to take part in a study on long-COVID. They want to find out why some people with lingering symptoms get better, and others end up with chronic health problems.

In Rawhide Down, journalist Del Quentin Wilber offers new information about the March 1981 day that President Ronald Reagan was shot in Washington, D.C. Wilber and Jerry Parr, the head of Reagan's Secret Service detail at the time of the shooting, speak with NPR's Ari Shapiro.

Author Ken Wells layers his new novel with love, corruption and Cajun cuisine. Jacki Lyden talks with Wells about Crawfish Mountain, a story about big oil and the Louisiana wetlands.