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Michael Kors is trying to shore up declining demand for expensive handbags and says it aims to double the annual sales of the smaller footwear and accessories brand.

The Cherokee Indians referred to the mountain as Kuwahi for hundreds of years, long before it was dubbed Clingmans Dome in 1859.

The Chilean air force says it hasn't been able to locate the Hercules C-130 transport plane but has determined it likely crashed. A search and rescue mission is ongoing.

The maker of one medical treatment for opioid abuse has successfully lobbied statehouses around the country to pass policies that tilt addiction treatment practices in favor of the company's drug.

The House has approved a spending bill to end a short-lived partial government shutdown. Now lawmakers will begin contentious negotiations over new guardrails for immigration enforcement.

Town of Normal staff has asked Town Council Member Stan Nord to halt development on his property in west Normal for a business until the town approves a…

Many insurers are restricting access to new drugs that are easier to take and that promise higher cure rates because the price tags can run $95,000 or more.

Abortion rights will be on the ballot in 10 states this November, meaning tens of millions of voters will decide whether to protect reproductive rights in their state constitutions.

Berezin studied physics but, despairing of the job market in physics, she turned to the rapidly transforming computer industry. She invented the first truly computerized system for word processing.

The presidential election has entered its closing arguments phase. Hillary Clinton seems to have the edge in key states and may even be expanding into states that have traditionally voted Republican.