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The Massachusetts-based biotech company had high hopes in the first Alzheimer's treatment in a generation earlier this year. But its approval and the lead-up to it are now under investigation.

The Senate is considering whether to approve an expensive and controversial stealth spy satellite program as part of an intelligence spending bill. Some leading Democrats have objected to it on the Senate floor, though they won't publicly identify what it is. NPR's Robert Siegel talks with John Pike, director of GlobalSecurity.org.

House Democrats release an analysis suggesting that at best, the cost of military operations in Iraq will add $179 billion to the federal deficit over the next decade. Meanwhile, Republicans vow to approve President Bush's $87 billion funding request for Iraq. Both parties call on the White House to be more upfront about expected Iraq-related costs. Hear NPR's Andrea Seabrook.

President Bush will address the United Nations Tuesday to ask for greater international support as the United States struggles to restore stability and self-government in Iraq. Bush's request will be complicated by tensions resulting from the U.S. decision to go to war in Iraq without the U.N. Security Council's approval. Hear NPR's Don Gonyea.

Federal Reserve policy-makers will likely approve a small increase in the short term interest rates it controls. The economy has been heating up and the Fed wants to keep inflation from getting out of hand. If the Fed does move tomorrow it will mean that a long period of historically low interest rates is coming to an end. NPR's Jim Zarroli reports.

The Senate ends the prospect of a constitutional amendment banning gay marriage, at least for this year. An attempt to cut off debate and proceed to a vote on the amendment won the backing of less than half the Senate, far short of the two-thirds needed to approve the amendment itself. Six Republicans voted with Democrats, defeating the effort 50-48. NPR's David Welna reports.

The Bush administration releases scores of documents reflecting internal discussions about interrogation methods for U.S.-held prisoners. The release comes as the administration makes its case that it never gave approval for the torture or abuse of detainees in Iraq, Afghanistan or Guantanamo Bay, Cuba. Hear NPR's Robert Siegel and NPR's Jackie Northam.

Vermont's Legislature overruled Republican Gov. Jim Douglas' veto and became the fourth state to legalize gay marriage. The Senate voted 23-5 and the House 100-49 to get the two-thirds needed in each chamber for a veto override. Nine years ago, Vermont was the first state in the nation to approve civil unions.

The Federal Reserve meets Tuesday to decide whether to lower a key interest rate. Over the weekend, the central bank approved a cut in its emergency lending rate to financial institutions and became a lender of last resort for investment houses to begin securing short-term emergency loans.

Oil company BP American says it will not immediately increase the amount of pollution it dumps into Lake Michigan from its refinery in Whiting, Ind., reversing earlier comments. The announcement follows weeks of uproar after the state approved BP's plan to dump 54 percent more ammonia into Lake Michigan.