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The man the U.S. alleges is the top al-Qaida operative who orchestrated the 1998 bombings of the U.S. embassies in Kenya and Tanzania has pleaded not guilty to the charges at a federal court in Manhattan. The case has brought the High Value Interrogation Group back into the spotlight. It was created by the Obama administration to extract valuable intelligence from terrorists, but national security experts say there have been too few cases to judge its promise.

The COVID-19 vaccine strategy may be shifting toward Americans getting yearly vaccinations, like many do with annual flu shots.

South Carolina Sen. Tim Scott has taken a significant step toward a presidential bid, launching an exploratory committee. Scott, 57, is the only Black Republican currently in the U.S. Senate.

Low-lying southwest Louisiana is particularly vulnerable to flooding from Hurricane Harvey, and some areas are evacuating as people head to higher ground.

New York City's art museum scene has gone to the dogs. The new American Kennel Club Museum of the Dog features life-sized sculptures and paintings of canines through the ages.

North Carolina is a crucial state that Republicans need to win if they are to take the White House this fall. But so far, Donald Trump's campaign has almost no presence there.

Ernest Gagnon, who once weighed 570 pounds, chose an unusual way to lose weight. Instead of surgery, he decided to take up cyclocross. He lost more than 200 pounds, and now he's even racing.

University of Vermont students are providing hands-on help to rural towns in the state. It's part of a trend to help build bridges between higher education and rural communities.

An investigation by the Los Angeles Times into labor camps on Mexican megafarms reveals appalling conditions. Reporter Richard Marosi says U.S. consumers need to pressure retailers for change.

The Biden administration has launched a new effort to improve the ability of the U.S. to prevent, detect and respond to global health threats. Some experts say the new strategy doesn't go far enough.