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Even as a child, Benjamin Carson wanted to be a doctor. Now a renowned pediatric neurosurgeon, Carson believes he owes his success to his mother, a domestic who received only a third-grade education.

New York City is increasing security on its subways after receiving what Mayor Mike Bloomberg calls a specific threat to mass transit in the coming days. At a press conference Thursday, he made note of an unusual "level of specificity" and said the threat originated overseas.

Supplies begin to reach earthquake-battered Pakistan. Eight U.S. helicopters are due Monday. More than 20,000 people are dead. U.N. official Vivian Tan and Ron Moreau of Newsweek tell Debbie Elliott what they're seeing.

The International Atomic Energy Agency and its chief, Mohamed ElBaradei, receive the 2005 Nobel Peace Prize. Matthew Bunn, acting executive director of the Project on Managing the Atom at Harvard University's John F. Kennedy School of Government, discusses the U.N. watchdog group and its work.

Los Angeles Mayor Antonio Villaraigosa is leading a task force on poverty for the U.S. Conference of Mayors. He tells Michele Norris about his plan to fight poverty, homelessness and other issues facing his city and others around the nation.

Scott Simon talks to Matt Shardlow of UK conservation group Buglife about the decline in flying invertebrates in the UK and how that could spell environmental disaster.

The federal judge issued a preliminary injunction while a court challenge goes forward. The judge left in place other parts of the law that banned gender-affirming surgeries.

The Supreme Court agrees to consider a challenge to the military tribunals the Bush administration has used to try suspected terrorists. One of the detainees includes a man captured in Afghanistan in 2001 and accused of being the driver for al Qaeda leader Osama bin Laden.

Egyptian President Hosni Mubarak is expected to win reelection next week, in the country's first multi-candidate presidential elections. Mubarak will face nine challengers, all of whom are struggling to get their message out.

President Bush delivers his fifth State of the Union address Tuesday night. The president is expected to talk about ways to reduce U.S. dependence on foreign oil, and control rising health care costs. Other key topics will include the war in Iraq, Iran's nuclear program and last week's Palestinian elections.